High prevalence of fluoroquinolone-resistant group b streptococci among clinical isolates in china and predominance of sequence type 19 with serotype III

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Abstract

A total of 146 group B streptococcus isolates from 8 cities across China belonged to four serotypes. Serotype Ia was more common in children. A high prevalence of resistance was observed for levofloxacin (37.7%), erythromycin (71.2%), clindamycin, (53.4%), and tetracycline (81.5%). The levofloxacin and clindamycin resistances among the 4 serotypes differed significantly. Eighty percent of fluoroquinolone-resistant isolates belonged to the sequence type 19 (ST19)/serotype III clone, with GyrAParC- ParE triple substitutions. This clone carried the erm(B), mef(E), and tet(M) genes. Copyright © 2013, American Society for Microbiology.

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Wang, H., Zhao, C., He, W., Zhang, F., Zhang, L., Cao, B., … Ni, Y. (2013). High prevalence of fluoroquinolone-resistant group b streptococci among clinical isolates in china and predominance of sequence type 19 with serotype III. Antimicrobial Agents and Chemotherapy, 57(3), 1538–1541. https://doi.org/10.1128/AAC.02317-12

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