Successful engraftment of human hepatocytes in uPA- SCID and FRG® KO mice

17Citations
Citations of this article
22Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Mice with humanized chimeric liver are promising in vivo tools to evaluate the efficacy of novel compounds or vaccine induced antibodies directed against pathogens that infect the human liver. In addition they can be used to study the human-type metabolism of medicinal compounds and hepatotoxicity.

Cite

CITATION STYLE

APA

Foquet, L., Wilson, E. M., Verhoye, L., Grompe, M., Leroux-Roels, G., Bial, J., & Meuleman, P. (2017). Successful engraftment of human hepatocytes in uPA- SCID and FRG® KO mice. In Methods in Molecular Biology (Vol. 1506, pp. 117–130). Humana Press Inc. https://doi.org/10.1007/978-1-4939-6506-9_8

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free