H1 gets the genome in shape

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Abstract

By performing high-throughput chromosome conformation capture analyses in embryonic stem cells depleted of the linker histone H1, Geeven and colleagues have uncovered exciting new evidence concerning a role for this histone in modulating three-dimensional genome architecture and chromatin organization.

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Izzo, A., & Schneider, R. (2016). H1 gets the genome in shape. Genome Biology, 17(8). https://doi.org/10.1186/s13059-016-0872-9

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