Is pulse pressure variation more accurate than central venous pressure (CVP) or pulmonary artery pressure (PAP) for volume resuscitation?

Abstract

A 48-year-old man on postoperative day 2 is recovering in the surgical intensive care unit from an extensive retroperitoneal sarcoma resection. The case was complicated by transfusion of 12 U of packed red blood cells, 6 U of fresh frozen plasma, and two packs of platelets. Due to the nature of his operation and the likely stormy postoperative course, it is decided to keep the patient sedated, intubated, and mechanically ventilated.