Selection of oleaginous yeasts for fatty acid production

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Abstract

Background: Oleaginous yeast species are an alternative for the production of lipids or triacylglycerides (TAGs). These yeasts are usually non-pathogenic and able to store TAGs ranging from 20 % to 70 % of their cell mass depending on culture conditions. TAGs originating from oleaginous yeasts can be used as the so-called second generation biofuels, which are based on non-food competing "waste carbon sources". Results: In this study the selection of potentially new interesting oleaginous yeast strains is described. Important selection criteria were: a broad maximum temperature and pH range for growth (robustness of the strain), a broad spectrum of carbon sources that can be metabolized (preferably including C-5 sugars), a high total fatty acid content in combination with a low glycogen content and genetic accessibility. Conclusions: Based on these selection criteria, among 24 screened species, Schwanniomyces occidentalis (Debaromyces occidentalis) CBS2864 was selected as a promising strain for the production of high amounts of lipids.

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Lamers, D., van Biezen, N., Martens, D., Peters, L., van de Zilver, E., Jacobs-van Dreumel, N., … Lokman, C. (2016). Selection of oleaginous yeasts for fatty acid production. BMC Biotechnology, 16(1). https://doi.org/10.1186/s12896-016-0276-7

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