Genetic analysis of sequence data is central to determining the evolutionary history and molecular epidemiology of viruses, particularly those such as influenza A virus that have complex ecosystems involving multiple hosts. Here we provide an outline of routine phylogenetic analyses of influenza A viruses including multiple sequence alignment, selecting the best-fit evolutionary model and phylogenetic tree reconstruction using Neighbor joining, Maximum likelihood, and Bayesian inference. © 2012 Springer Science+Business Media, LLC.
CITATION STYLE
Smith, G. J. D., Bahl, J., & Vijaykrishna, D. (2012). Genetic analysis. Methods in Molecular Biology, 865, 207–227. https://doi.org/10.1007/978-1-61779-621-0_13
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