Candida spp. proliferate as surface-associated biofilms in a variety of clinical niches. These biofilms can be extremely difficult to eradicate in healthcare settings. Cells within biofilm communities grow as aggregates and produce a protective extracellular matrix, properties that impact the ability of the host to respond to infection. Cells that disperse from biofilms display a phenotype of enhanced pathogenicity. In this review, we highlight host-biofilm interactions for Candida, focusing on how biofilm formation influences innate immune responses.
CITATION STYLE
Eix, E. F., & Nett, J. E. (2020, June 25). How Biofilm Growth Affects Candida-Host Interactions. Frontiers in Microbiology. Frontiers Media S.A. https://doi.org/10.3389/fmicb.2020.01437
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