AlGaN/GaN High Electron Mobility Transistors for Cardiovascular Disease (CVD) Marker Detection

Abstract

According to the statistics published by the World Health Organization (WHO) in 2011, cardiovascular disease (CVD) is the leading cause of death globally. Recent studies suggest that the level of C-reactive protein can be an important indicator of a person’s risk for cardiovascular disease. In this study, we detect low concentration of C-reactive protein (1 fM) electronically by immobilizing CRP-specific aptamer on the AlGaN/GaN HEMT based biosensor, showing that this technique is promising for biosensor applications.