Induced Pluripotent Stem Cells in Disease Modelling and Regeneration

Abstract

The reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) has raised extreme hope among both scientists and society by means of development of personalized and regenerative medicine. The field of stem cell research has been accelerating with a drastic speed afterwards and many iPSC lines has been produced for understanding the mechanisms of many debilitating diseases which arise in a variety of organ systems. In this review article we try to focus on the current research regarding the use of iPSCs in both disease modeling and regeneration.