In this issue of Genes & Development, Dowen and colleagues (pp. 1515-1528) elegantly unify two previously unconnected aspects of physiology. The investigators provide significant genetic evidence to support a critical link between developmental timing decisions and the regulation of lipid mobilization at the transition to adulthood in Caenorhabditis elegans. This novel connection involves cross-tissue signaling fromthe hypodermis (epidermis) to the intestine to promote reproductive success in the germline.
CITATION STYLE
Weaver, B. P., Sewell, A. K., & Han, M. (2016). Time to move the fat. Genes and Development, 30(13), 1481–1482. https://doi.org/10.1101/gad.285460.116
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