Kinetics of cyclophosphamide and ifosfamide degradation from aqueous system via TiO2 assisted photocatalysis

Abstract

Cyclophosphamide (CP)-N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-Amine 2-oxide and ifosfamide (IF)-N,3-bis(2-chloroe thyl)-1,3,2-oxazaphosphinan-2-Amide 2-oxide degradation unde r UV-Vis/TiO2 photocatalysis was studied in the following experimental conditions: photocatalyst dose = 100 - 800 mg/ L; irradiation time = 30-360 min; initial pollutant concentration = 1 - 50 mg/L. CP and IF degradation via TiO2 photocatalysis was found to obey Langmuir - Hinshelwood model and pollutants degradation rate constants: 5.89 x 10-6 M min-1 (CP); 4.86 × 10-6 M min-1 (IF) and pollutants adsorption - desorption on TiO2 particles equilibrium constants: 5637 M-1 (CP); 4930 M-1 (IF) were calculated.