Langerhans cell histiocytosis comprises a set of conditions ranging from a localized form represented by a solitary lesion to a disseminated multiorgan involvement and having in common the microscopic findings of foci of proliferating Langerhans cells. Variants include eosinophilic granuloma (localized disease), Hand—Schuller—Christian (disseminated form), and Letterer—Siwe disease (disseminated and fatal form).
CITATION STYLE
Kalil, R. K. (2015). Langerhans cell histiocytosis. In Tumors and Tumor-Like Lesions of Bone: For Surgical Pathologists, Orthopedic Surgeons and Radiologists (pp. 805–813). Springer-Verlag London Ltd. https://doi.org/10.1007/978-1-4471-6578-1_58
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