The differences of cell biology in the repair process of wound and refractory wound surface

Abstract

In the following paragraph we will discuss the differences of the cell biology in the repair process of wound and refractory wound surface. In the repair process of wound surface the cell biology in hemostasis phase, in inflammation phase, in proliferation, angiogenesis, fibroplasia and epithelialization phase and in contraction, maturation and remodeling phase in the normal organ or tissue such as skin after injury will be shown. The cell biology in the repair process of refractory wound surface, we mainly discuss the cell biology in refractory wound surface of the diabetes such as the effect of diabetes on the biological function of fibroblasts, M1/M2 macrophage imbalance in the repair process of refractory wound surface of diabetic, the effect of glycosylated extracellular matrix on fibroblasts and so on.