“Seed and Soil” Theory of Metastasis

Abstract

Is a low molecular weight protein normally present in cells derived from the neural crest (Schwann S1P Definition Sphingosine-1-phosphate, an anti-apoptotic, angio-genic sphingolipid. A pro-proliferative sphingolipid that counteracts ceramide effects. ▶ Sphingolipid Metabolism S-9 Definition Is a cell free fraction derived from a chopped up liver that performs mostly ▶ phase II metabolism on a drug. ▶ ADMET Screen SAAB Definition Selected and amplification binding (SAAB) is a combinatorial selection method that makes use of preliminary information regarding a ligand's binding specificity when designing a selection template. Unlike other combinatorial selection methods, SAAB does not require subcloning of selected templates but rather obtains binding specificity through direct sequencing of the selected template pool. ▶ Combinatorial Selection Methods SAGE Definition Serial analysis of gene expression (SAGE) is a method that allows the analysis of overall gene expression patterns with digital analysis. SAHA Definition Suberoylanilide hydroxamic acid, an inhibitor of his-tone deacetylases.