A simple preparation of ethyl 2,5-dimethylfuran-3-carboxylate and 2,5-dimethylfuran-3,4-dicarboxylic acid from diethyl 2,3-diacetylsuccinate

Abstract

(Chemical Equation Presented) A simple preparation of ethyl 2,5-dimethylfuran-3-carboxylate (3), 2,5-dimethylfuran-3,4-dicarboxylic acid (4), and diethyl 2,5-dimethylfuran-3,4-dicarboxylate (5) by treatment of diethyl 2,3-diacetylsuccinate (2) with aqueous HCl is reported. The reaction is performed under organic solvent free conditions from a readily available cheap starting material. © 2009 HeteroCorporation.