Fisiología de la coagulación

Abstract

Hemostasis is the process that maintains the integrity of a closed, high-pressure circulatory system after vascular damage. For study purpose is divided into primary and secondary. Primary hemostasis refers to the processes by which the platelet plug is formed through adhesion, activation, secretion, and platelet aggregation. Secondary hemostasis involves activation of the enzyme system whose major objective is the formation of thrombin and fi brin for clot stabilization. Finally there is the process of fi brinolysis, which is responsible for removing the remains of the clot once repaired tissue damage. These systems under physiological conditions maintain a perfect balance and when lost, lead to a pathological condition, such as bleeding or thrombosis.