Dedicated mouse production and husbandry

Abstract

The complexity of mammalian biology, in combination with the ability to manipulate the embryonic genome in mice, has provided specific challenges in terms of mouse breeding, analysis, and husbandry. From the initial planning stage of a project involving the generation of novel, genetically altered mice, it is important to consider a number of potential issues involving the successful establishment and propagation of a transgenic line. © 2009 Humana Press, a part of Springer Science+Business Media, LLC.