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The relationship between interleukin-6 in saliva, venous and capillary plasma, at rest and in response to exercise

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Abstract

IL-6 plays a mechanistic role in conditions such as metabolic syndrome, chronic fatigue syndrome and clinical depression and also plays a major role in inflammatory and immune responses to exercise. The purpose of this study was to investigate the levels of resting and post exercise IL-6 when measured in venous plasma, saliva and capillary plasma. Five male and five females completed 2 separate exercise trials, both of which involved standardized exercise sessions on a cycle ergometer. Venous blood and saliva samples were taken immediately before and after Trial A, venous and capillary blood samples were taken immediately before and after Trial B. IL-6 values were obtained using a high-sensitivity enzyme-linked immunosorbent assay (ELISA). In Trial A venous plasma IL-6 increased significantly from 0.4. ±. 0.14. pg/ml to 0.99. ±. 0.29. pg/ml (. P

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Cullen, T., Thomas, A. W., Webb, R., & Hughes, M. G. (2015). The relationship between interleukin-6 in saliva, venous and capillary plasma, at rest and in response to exercise. Cytokine, 71(2), 397–400. https://doi.org/10.1016/j.cyto.2014.10.011

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