Models of Tumor Growth

Abstract

In 2016 the World Health Organization provided the most recent classification of tumors of the central nervous system based on histology, molecular mechanisms, rate of brain invasion, and a soft tissue-type grading system. The classification of various benign and malignant brain tumors can be used as well as improved by the integration of in silico, in vitro and in vivo studies of brain tumors that will ultimately lead to better diagnosis, treatment protocols and outcomes. In this chapter we review some of the modeling approaches proposed in the literature to predict tumor growth and therapeutic outcome.