Prevention of Perinatal Group B Streptococcus Infections

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Abstract

Group B streptococcus (GBS) is a leading cause of neonatal infection. Maternal vaginal-rectal colonization with GBS during the intrapartum period is a prerequisite for GBS early-onset disease (EOD). The obstetric measures for effective prevention of GBS EOD include universal prenatal screening by vaginal-rectal culture, correct specimen collection and processing, appropriate implementation of intrapartum antibiotic prophylaxis, and coordination with pediatric care providers. It is now recommended to universal screen GBS between 360/7and 376/7weeks of gestation and to identify groups of women who are eligible for intravenous intrapartum antibiotic prophylaxis as a means of preventing GBS EOD.

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Fan, S. R., Tasneem, U., Liu, X. P., & Yan, S. M. (2020). Prevention of Perinatal Group B Streptococcus Infections. Maternal-Fetal Medicine. Wolters Kluwer Health. https://doi.org/10.1097/FM9.0000000000000041

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