This chapter discusses protein-based nanoscale actuation mechanisms with two illustrative examples, the viral protein linear nanoActuator and the GCN4 peptide nanoActuator. The VPL peptide is based on the conformation change mechanism of envelope glycoprotein of naturally occurring retroviruses. The GCN4 is an artificial design based on two helical coils. Structural features, stability, and optimal design considerations are described in detail. Computational methods are applied to gain knowledge about a given molecule and its suitability to function as a nanoActuator.
CITATION STYLE
Sharma, G., Dubey, A., & Mavroidis, C. (2013). Protein-based nanoscale actuation. In Nanorobotics: Current Approaches and Techniques (pp. 425–455). Springer New York. https://doi.org/10.1007/978-1-4614-2119-1_21
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