Bacteriological and clinical profile of community acquired pneumonia in hospitalised children with associated co-morbidity in a tertiary care centre of Western Rajasthan, India

Abstract

Context: Community acquired pneumonia (CAP) is still a significant cause of morbidity and mortality throughout the world despite availability of potent antimicrobials. Aims: The objective of our study was to look into the bacteriological and clinical profile of CAP patients requiring admission in our tertiary care hospital in Kolkata, West-Bengal. Settings and Design: This was a prospective, observational, cross sectional study comprising of 128 patients admitted in chest ward with CAP. Methods and material: At the time of admission a detailed history and clinical examination, chest radiography, complete hemogram, glycemic status, renal and liver function tests were done in all patients. Sputum sample was collected for gram staining and bacteriological culture on blood agar and MacConkeys agar media. Two blood samples were sent for culture. Statistical analysis used: Predesigned and pretested schedule for collection of baseline informations. For statistical analysis multiple logistic regression were performed with SPSS programme version 16. Results: Our results showed that mean age was 42.13± 9.8yrs with male predominance (M:F 2.28:1). The commonest presenting symptom was cough, whereas the commonest clinical sign was tachypnea. Microorganism could be isolated in sputum culture in 75% of cases, but yield of blood culture was low(9%). The commonest microorganism isolated was Streptococcus Pneumonia in 41% cases followed by Pseudomonas in 11% cases. In diabetic patients, the commonest organism was Streptococcus Pneumonia (28%), but proportion of Klebsiella species was also high(16%). Conclusion: The present study showed that microorganisms can be isolated in significant number of cases of CAP in sputum culture, but the yield of blood culture is low. The microbiological pattern in samples may differ, but knowledge of distribution in certain