Short-term effects of sleeve gastrectomy on weight loss and diastolic function in obese patients

Abstract

Objective: Bariatric surgery has been shown to improve cardiac structure and function in obese patients. This study was an examination of the short-term effects of sleeve gastrectomy on body measurements and diastolic function. Methods: A total of 41 consecutive obese patients who were scheduled to undergo a sleeve gastrectomy procedure were included in the study. Baseline body and echocardiographic measurements and the follow-up counterpart data, including total and excess weight loss percentages, were recorded. Results: The mean age of the patients was 42.85±11.47 years. Of the total, 21 (51.1%) patients were female. The mean body mass index (BMI) was 44.86±5.62 kg/m2. The mean duration of follow-up was 91.24±44.48 days. The participants demonstrated statistically significant weight loss (26.64±10.95 kg), as well as a decrease in BMI (8.84±3.93 kg/m2) and body surface area (0.27±0.12 m2). A significant increase in E velocity and mitral annular e velocity were observed, as well as a significant decrease in A velocity, E/e ratio, left ventricle mass, and left atrial volume (LAV). No significant correlations between the body measurement changes and changes in echocardiographic parameters were observed, with the exception that the excessive weight loss percentage was moderately correlated with a change in LAV. Conclusion: Sleeve gastrectomy led to a significant decrease in body weight and improved diastolic function parameters in the short-term. No significant relationship was found between the amount of weight loss and change in echocardiographic measurements.