Bioprospecting for lipophilic-like components of five Phaeophyta macroalgae from the Portuguese coast

Abstract

Lipophilic compounds present in dichloromethane extracts of five brown macroalgae from the Portuguese coast were analyzed by gas chromatography-mass spectrometry (GC-MS). Their dicarboxylic acids, long-chain aliphatic alcohols, and monoglyceride profile are reported for the first time. Additionally, other new compounds were also first reported: 24-methylene-cholesterol in Himanthalia elongata, Laminaria ochroleuca, and Undaria pinnatifida; desmosterol and brassicasterol in H. elongata, L. ochroleuca, Sargassum muticum, and U. pinnatifida; fucosterol and campesterol in S. muticum; and cholest-5-en-3-ol-(3β)-3-phenyl-2-propenoate in Cystoseira tamariscifolia. Brown macroalgae dichloromethane extracts are mainly composed of fatty acids (463.4–3089.0 mg kg−1 of dry material) and sterols (75.5–442.7 mg kg−1 of dry material). High amounts of polyunsaturated fatty acids were found, with the ω-6/ω-3 ratios of all species lower than 3. Cystoseira tamariscifolia, H. elongata, and S. muticum showed to be also promising sources of fucosterol. These results seem to uphold the incorporation of these macroalgae in a more balanced diet, as well as their use in the nutraceutical industry, as long as they are coupled with sustainable management of these natural resources.