Iron-catalyzed C-H fuctionalization of indoles

Abstract

An easily available iron catalyst was developed to accomplish the C-H functionalization of indoles with α-aryl-α-diazoesters in high yields under mild conditions. The asymmetric C-H functionalization of indoles was also realized by using iron complexes of chiral spiro bisoxazolines with up to 78% ee. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.