Chemotherapy-related visual system toxicity

Abstract

Most, if not all, of the studies that report cognitive impairments in patients who have been treated with cancer chemotherapy also report deficits involving the visual system (e.g., visual-spatial function or visual memory). The visual system seems like a likely susceptible target of cytotoxic drugs. Therefore, some portion of the vision-related cognitive deficits of chemo fog/chemo brain might result from a direct action of the drugs or from site/site interaction between effects on the visual system and other critical brain regions. This chapter is a succint summary of a more expanded review.1 © 2010 Landes Bioscience and Springer Science+Business Media.