The biosynthesis of murein occurs in three stages, which take place in (1) the cytoplasm forming muropeptide precursors, (2) the inner side of the cytoplasmic membrane involving the undecaprenyl-phosphate carrier lipid, and (3) the periplasm where the assembly of the macromolecule takes place. Antibiotics involved in the different steps of murein biosynthesis are described in this chapter. © 2010 Springer-Verlag Berlin Heidelberg.
CITATION STYLE
Hakenbeck, R., Brückner, R., & Henrich, B. (2010). Cell wall targeted antibiotics. In Prokaryotic Cell Wall Compounds: Structure and Biochemistry (pp. 347–381). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-05062-6_12
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