DNA methylations, including global methylation pattern and specific gene methylation, are associated with pathogenesis and progress of pulmonary fibrosis. This chapter illustrates alteration of DNA methylation in pulmonary fibrosis as a predictive or prognostic factor. Treatment with the DNA methylation inhibitors will be an emerging anti-fibrosis therapy, although we are still in the pre-clinical stage of using epigenetic markers as potential targets for biomarkers and therapeutic interventions.
CITATION STYLE
Zhou, S., Wang, X., Gao, H., & Zeng, Y. (2020). DNA methylation in pulmonary fibrosis. In Advances in Experimental Medicine and Biology (Vol. 1255, pp. 51–62). Springer. https://doi.org/10.1007/978-981-15-4494-1_4
Mendeley helps you to discover research relevant for your work.