INstruct: A database of high-quality 3D structurally resolved protein interactome networks

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Abstract

INstruct is a database of high-quality, 3D, structurally resolved protein interactome networks in human and six model organisms. INstruct combines the scale of available high-quality binary protein interaction data with the specificity of atomic-resolution structural information derived from co-crystal evidence using a tested interaction interface inference method. Its web interface is designed to allow for flexible search based on standard and organism-specific protein and gene-naming conventions, visualization of protein architecture highlighting interaction interfaces and viewing and downloading custom 3D structurally resolved interactome datasets. © 2012 The Author.

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Meyer, M. J., Das, J., Wang, X., & Yu, H. (2013). INstruct: A database of high-quality 3D structurally resolved protein interactome networks. Bioinformatics, 29(12), 1577–1579. https://doi.org/10.1093/bioinformatics/btt181

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