Salting out and ionic gelation manufacturing techniques for nanoparticles

Abstract

Nanotechnology is currently most explored filed by the researchers especially in novel drug development. Polymeric nanoparticles are the nanomedicine developed by employing nanotechnology in the field of pharmaceutical drug development. Polymeric nanoparticles have many advantages such as less toxicity, targeted drug delivery in several types of diseases include cancer, diabetes, gastrointestinal diseases, pulmonary diseases, and others. The current chapter mainly focused on the various polymers that are used to prepare the nanoparticles. The methodology of different techniques available for the preparation of various kinds of synthetic and natural polymers was discussed focusing mainly on salting-out and ionic gelation crosslinking methods. Further, the latest technologies introduced by the researchers in the recent past for the preparation of polymeric nanoparticles to overcome the limitations of traditional methods are being discussed briefly in the current chapter.