A neuromuscular transmission disorder: combined myasthenia gravis and Lambert Eaton syndrome in one patient

Abstract

The distinction between myasthenia gravis and Lambert Eaton myasthenic syndrome can usually be made by the clinical and neurophysiological features. A patient was observed with features which suggested a combination of both disorders. This has been described in few patients before. The importance of electromyography in both distal and proximal limb muscles for a correct diagnosis is demonstrated. Only in proximal nerve stimulation tests was proof found of the existence of both syndromes.