Development of a new vascular endoscopic system for observing inner wall of aorta using intermittent saline jet

Abstract

A prototype endoscopic system for observing inner wall of aorta was developed and tested in vivo using swine. The purpose of this system is to visualize the inner wall of aorta without stopping aortic flow for the use of an assistive technique for endovascular interventions such as stent-graft placement for aortic aneurysm. The technique newly introduced for this purpose was the use of intermittent highpressure saline jet synchronized to heart beat (diastolic phase). For preliminary studies, a commercially available bronchoscope having an outer diameter of 5mm with a biopsy channel was used, and a discharging system for intermittent highpressure saline jet was constructed using a high-speed solenoid valve and a pressurizing tank. From in vitro tests, it was confirmed that we could obtain sufficient amount of saline jet (about 1ml) within short period of time (about 100 ms) with the driving pressure of 0.1 MPa. Based on these results, we conducted in vivo tests using swine with the body weight of about 30 kg. The tip of the endoscope was introduced from the abdominal aorta and inserted proximally about 30 cm. At this point, the saline jet was discharged (period: 200 ms, driving pressure: 0.2 MPa), and then we could clearly observe the aortic bifurcations during the flushing period. This result strongly suggests an availability of the present method as an assistive technology for the endovascular interventions in aorta.