We report the results of an empirical study of 256 paternity cases referred to 7 different German laboratories for DNA fingerprinting with oligonucleotide probe (CAC)5/(GTG)5. All parameters characteristic of such multilocus DNA fingerprints were found to differ significantly between the contributing centres. Despite these differences, clear-cut decisions between paternity and non-paternity could be made in all but one case. Furthermore, we found no systematic deviation of the gel-phenotype distribution among trios from random expectation as derived from commonly adopted analytical models. Thus, we conclude that oligonucleotide DNA fingerprinting is a robust and reliable means for the resolution of paternity cases.
CITATION STYLE
Böhm, I., Krawczak, M., Nürnberg, P., Hampe, J., Hundrieser, J., Pöche, H., … Nagy, M. (1993). Oligonucleotide DNA fingerprinting: results of a multi-center study on reliability and validity. EXS, 67, 257–260. https://doi.org/10.1007/978-3-0348-8583-6_22
Mendeley helps you to discover research relevant for your work.