Establishment of an experimental model of human hepatoblastoma

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Abstract

Establishment of xenografts or cell culture lines in which the α‐fetoprotein (AFP) characteristic of clinical hepatoblastoma persists have been difficult. The serially transplantable strain (HB‐3) of highly AFP‐producing hepatoblastoma was successfully established in nude mice. And a highly AFP producing cell line (c‐HB‐3) is easily obtained by HB‐3. This strain and line give us an ideal experimental model of hepatoblastoma in vivo and in vitro. Cancer 50:97–101, 1982. Copyright © 1982 American Cancer Society

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APA

Hata, Y., Uchino, J., Sato, K., Sasaki, F., Une, Y., Naito, H., … Kasai, Y. (1982). Establishment of an experimental model of human hepatoblastoma. Cancer, 50(1), 97–101. https://doi.org/10.1002/1097-0142(19820701)50:1<97::AID-CNCR2820500118>3.0.CO;2-4

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