Abstract
Antibody decline occurred from 2 weeks to 6 months post-BNT162b2 mRNA vaccination in nursing home (NH) residents and healthcare workers. Antispike, receptor-binding domain, and neutralization levels dropped >81% irrespective of prior infection. Notably, 69% of infection-naive NH residents had neutralizing antibodies at or below the assay's limit of detection.
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Canaday, D. H., Oyebanji, O. A., Keresztesy, D., Payne, M., Wilk, D., Carias, L., … Gravenstein, S. (2022). Significant Reduction in Vaccine-Induced Antibody Levels and Neutralization Activity among Healthcare Workers and Nursing Home Residents 6 Months Following Coronavirus Disease 2019 BNT162b2 mRNA Vaccination. Clinical Infectious Diseases, 75(1), E884–E887. https://doi.org/10.1093/cid/ciab963
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