Leucoencefalopatía Hipóxica Tardía tras Autointoxicación: del Abordaje Psiquiátrico al Neurológico

Abstract

The Delayed Hypoxic Leukoencephalopathy is a rare and still unknown pathogenesis process that provokes the appearance of acute confusional symptomatology and cognitive deterioration after a period of 2 to 10 days of apparent complete recovery from hypoxia. In some cases, acute psychiatric symptoms, including apathy, anxiety and even the development of psychosis, have been observed. Mainly associated with carbon monoxide poisoning, these symptoms have also been found as secondary to self-poisoning with toxic and psychotropic drugs that cause prolonged hypotensive episodes. The number of published cases and the literature on the subject is really scanty. The rare case, within four years, of two patients with a prior mental disorder who entered Psychiatric Inpatients Unit after autointoxication, is collected in these clinical notes. They develop, from a psychiatric perspective, the concepts of this unknown clinic entity and the inevitable passage from the psychiatric approach to neurological. (English) [ABSTRACT FROM AUTHOR]