Potential applications of glycosaminoglycan-related compounds in Alzheimer's disease

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Abstract

Amyloid refers to extracellular proteinaceous fibrillar tissue deposits having a unique set of morphologic, tinctorial, ultrastructural, and protein-folding characteristics (Kisilevsky, 1996). Up to now, more than 25 amyloid proteins or peptides have been identified, each being associated with one type of amyloid deposit (for a review see: Westermark et al., 2005).

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Morissette, C., Lacombe, D., Kong, X., Aman, A., Krzywkowski, P., Rodionova, L., … Greenberg, B. D. (2007). Potential applications of glycosaminoglycan-related compounds in Alzheimer’s disease. In Pharmacological Mechanisms in Alzheimer’s Therapeutics (pp. 255–273). Springer New York. https://doi.org/10.1007/978-0-387-71522-3_16

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