West Nile virus encephalitis in haematological setting: Report of two cases and a brief review of the literature

6Citations
Citations of this article
18Readers
Mendeley users who have this article in their library.

Abstract

West Nile virus is a zoonotic agent causing life-threatening encephalitis in a proportion of infected patients. Older age, immunosuppression, and mutations in specific host genes (e.g., CCR5 delta-32 mutation) predispose to neuroinvasive infection. We report on two cases of severe West Nile encephalitis in recently-treated, different-aged, chronic lymphocytic leukemia patients. Both patients developed high-grade fever associated with severe neurological impairment. The younger one harboured germ-line CCR5 delta-32 mutation, which might have played a role in the pathogenesis of its neuroinvasive manifestations.

Cite

CITATION STYLE

APA

Ferrarini, I., Rigo, A., Gandini, A., & Vinante, F. (2019). West Nile virus encephalitis in haematological setting: Report of two cases and a brief review of the literature. Mediterranean Journal of Hematology and Infectious Diseases, 11(1). https://doi.org/10.4084/MJHID.2019.033

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free