Dosimetric considerations for stereotactic body radiotherapy delivery in the Lung

Abstract

In the performance of stereotactic body radiotherapy (SBRT), one must take into consideration not only the biology of the cancer being treated, but the physics and dosimetry behind delivery of the radiation dose. In a sense, investigation of the clinical application has begun before the basic research has been performed. Investigation of the biology of large-fraction radiotherapy has only started, but due to its potential for significant toxicity, extremely stringent conditions must be applied after due consideration. Here we examine some of the issues. © 2007 Springer-Verlag Berlin Heidelberg.