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p53 restoration

  • Novak K
Nature Reviews Cancer (2002) 2(3) 159-159
DOI: 10.1038/nrc771
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Abstract

More than 50% of human tumours carry mutations in TP53, so strategies to restore the activity of this tumour suppressor in cancer cells are being actively investigated by drug companies. A team of researchers in Sweden and Russia now report the discovery of a compound that reactivates p53 function and induces apoptosis in human cancer cells.

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Novak, K. (2002). p53 restoration. Nature Reviews Cancer, 2(3), 159–159. https://doi.org/10.1038/nrc771

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