Treatment-refractory schizophrenia: Definition and assessment

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Abstract

One third of people with schizophrenia don’t respond to standard treatments. The limited anti-psychotic options thereafter mean careful assessment of the presenting problem and assessment of response to and tolerance of previous treatment is essential, along with delineation of physical and mental health co-morbidities. This chapter will expand on the definitions of refractory schizophrenia and suggest a model for clinical assessment in practice.

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Tracy, D. K., & Shergill, S. S. (2014). Treatment-refractory schizophrenia: Definition and assessment. In Treatment-Refractory Schizophrenia: A Clinical Conundrum (pp. 1–20). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-45257-4_1

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