Prophylactic cyclo-oxygenase inhibitor drugs for the prevention of morbidity and mortality in preterm infants: a network meta-analysis

Abstract

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To determine the comparative effectiveness and safety of prophylactic cyclo-oxygenase inhibitor (COX-I) drugs (indomethacin, ibuprofen, or acetaminophen) and 'no COX-I prophylaxis' in preterm infants, using a Bayesian network meta-analysis.