Greener and facile aqueous synthesis of pyrazoles using Amberlyst-70 as a recyclable catalyst

Abstract

An environmentally benign, room temperature aqueous synthesis of pyrazoles by the condensation of hydrazines/hydrazides with 1,3-diketones using Amberlyst-70 as a recyclable catalyst is described. The use of resinous, non-toxic, thermally stable and inexpensive Amberlyst-70 as a heterogeneous catalyst and simple reaction workup are the additional eco-friendly attributes of this synthetic protocol. © 2012 Copyright Taylor and Francis Group, LLC.