The N270 in Facial S1-S2 Paradigm as a Biomarker for Children with Attention-Deficit/Hyperactivity Disorder

Abstract

Children with attention-deficit/hyperactivity disorder (ADHD) might suffer from dysfunctions that affect their social interaction, however, this issue has been less investigated and the results were inconclusive, especially for face processing. Applying event-related potential technology, the current study used modified facial S1-S2 paradigm to investigate face recognition in children with ADHD and health control group. Twenty-nine ADHD children and twenty-nine health children were recruited. The results showed that central N270 was delayed under inconsistent condition than consistent condition for ADHD group and no significant difference was revealed between ADHD group and control group on amplitude and latency of N170, N270. N270 might be a sensitive neurophysiological marker for ADHD children.