Evaluation of muscle dynamic response measured before and after treatment of spastic muscle with a BTX-A - A case study

Abstract

Contraction properties of spastic muscle has been evaluated using tensiomyographic method before and after treatment of spastic muscles with BTX-A. Significant differences are observed in TMG responses of a spastic muscle of cerebral origin before and after treatment with BTX-A. Typically, a TMG parameter Dm increases while time related TMG parameters Tr and Ts decrease after treatment of a muscle with a BTX-A. A parameter Tr/Dm has been found the most sensitive to changes of the muscle’s contractile properties. It is expected that the method can be used for determining muscle selection and therefore more effective use of expensive medicine and to evaluate the efficiency of the treatment.