Abstract
A game-changing therapy for peritoneal metastasis (PM), now called ‘comprehensive treatment’ was first established in the late 1990s. The treatment consists of aggressive cytoreductive surgery (CRS) combined with perioperative intraperitoneal/systemic chemotherapy. PM is considered as local disease, and the rationale behind the treatment is to remove macroscopic tumors and eradicate residual micrometastasis using perioperative chemotherapy (POC). Comprehensive treatment consists of laparoscopic evaluation of the tumor load, POC, and CRS. POC includes six procedures including laparoscopic hyperthermic intraperitoneal chemotherapy (LHIPEC), neoadjuvant intraperitoneal/systemic chemotherapy (NIPS), hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC).
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CITATION STYLE
Yonemura, Y., Mizumoto, A., Ishibashi, H., Takeshita, K., Glehen, O., & Sugarbaker, P. H. (2016). A new comprehensive treatment for peritoneal metastases using cytoreductive surgery combined with hyperthermic intraperitoneal chemoperfusion. In Hyperthermic Oncology from Bench to Bedside (pp. 371–396). Springer Singapore. https://doi.org/10.1007/978-981-10-0719-4_34
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