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High Resolution Computed Tomography Scoring Systems for Evaluating Interstitial Lung Disease in Systemic Sclerosis Patients

  • Assayag D
  • Kaduri S
  • Hudson M
Rheumatology : Current Research (2012) 01(S1)
DOI: 10.4172/2161-1149.s1-003
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Abstract

Interstitial lung disease commonly develops in patients with Systemic sclerosis (SSc). High resolution computed tomography (HRCT) has become the gold standard for detection and evaluation of lung involvement in SSc. Several HRCT scoring methods have been described and used to characterize and quantify the disease. This article reviews the different scoring systems and how they have been validated clinically and applied to prognosticate patients, assess disease progression and evaluate response to treatment.

Figures

  • Figure 1: Typical HRCT abnormalities in SSc-ILD. A. Pure ground glass opacities can be seen peripherally, predominantly in the right middle and left lower lobes; B. Subpleural thickened reticular markings are associated with traction bronchiectasis and bronchiolectasis; C. Ground glass opacities are mixed with fine reticular septal thickening diffusely; D. Extensive macrocystic honeycombing has replaced most of the left lower lobe and is associated with significant volume loss.
  • Table 4: Semi-quantitative scoring; Scleroderma Lung Study [27].
  • Figure 2: HRCT scan of a patient with SSc-ILD. This figure represents four cuts of an HRCT for a patient with SSc: A. Level of the aortic arch; B. Main carina; C. Pulmonary venous confluence; D. Origin of the diaphragm. The disease is more severe in the lower lung zones, with more pronounced reticular fibrosis and peripheral honeycombing.

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APA

Assayag, D., Kaduri, S., & Hudson, M. (2012). High Resolution Computed Tomography Scoring Systems for Evaluating Interstitial Lung Disease in Systemic Sclerosis Patients. Rheumatology : Current Research, 01(S1). https://doi.org/10.4172/2161-1149.s1-003

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