Serology

Abstract

Serological diagnosis is noninvasive and relatively economic and has less possibility of showing false-negative results in the situations of hemorrhagic ulcer or taking medications like antibiotics. In addition, it performs mass epidemiological survey simultaneously. However, it is not recommended for monitoring changes after antimicrobial treatment because this diagnosis hardly differentiates past Helicobacter pylori (H. pylori) infection and current active infection. There are various types of serological diagnoses of H. pylori existence such as bacterial agglutination, complement fixation, indirect immunofluorescence test (IIF), enzyme immunoassay (EIA), and enzyme-linked immunosorbent assay (ELISA). Among those, ELISA is the most popular method in the world.