P3.336 Seroprevalence of Human Immunodeficiency Virus (HIV)Infection Amongst Tuberculosis(TB) Patients Attending TB/DOTS Centre in Nnewi South East Nigeria

Abstract

Background: The Nnamdi Azikiwe University Teaching Hospital (NAUTH) Nnewi is a centre for free laboratory and x-ray investigations, management of tuberculosis and HIV infection in the South Eastern Nigeria. Method The authors conducted a retrospective study using the medical records of patients aimed at determining the prevalence of HIV infection in Tuberculosis (TB) patients attending Directly Observed Treatment Short-course (DOTS) services between April 2008 and December 2010. Pattern of TB/HIV co-infection rate over time was also analysed. Result The study showed a high prevalence of HIV among TB patients (29.9%). Smear Positive (SPT) was the most frequent (60.6%) form of TB diagnosis. Extra Pulmonary Tuberculosis (EPT) and Smear Negative Tuberculosis (SNT) were frequently associated with HIV co-infection (60.9%) and (62.9%) respectively. HIV prevalence and TB was higher in females (15.6%) than males (14.1%) though not statistically significant. Conclusion(s): The co-infection rate was highest among individuals aged 27-34 years(10.9%) followed by 35-42 years (8.1%) and least among 60 years and above (0.6%). The increase in TB/HIV co-infection rate was monotonic over time with a strong trend among females aged 27-34 years(25.7%,21.6% and 21.3%) for 2008,2009 and 2010 respectively.