Characterization of targets for antiviral therapy of Flaviviridae infections

Abstract

The members of the Flaviviridae family are the cause of the explosively increasing number of emerging infections of humans and economically important animals. Up to date there is no existing effective therapy targeting theses viruses. Recently obtained knowledge about the replication cycle and molecular organization of the Flaviviridae helps to understand the mechanisms by which the propagation of the viruses could be blocked. In this chapter the state of art regarding information about possible targets for antiviral strategies will be summarized.